4.6.0.0. Di­ag­nos­tic Tests for Susp. Hy­popi­tu­itarism

Table 2.2—Cri­te­ria for the di­ag­no­sis of di­a­betes

FPG ≥126 mg/dL (7.0 mmol/‍L). Fast­ing is de­fined as no caloric in­take for at least 8 h.*

OR

2-h_PG ≥200 mg/dL (11.1 mmol/‍L) dur­ing OGTT. The test should be per­formed as de­scribed by the

WHO, using a glu­cose load con­tain­ing the equiv­a­lent of 75-g an­hy­drous glu­cose dis­solved in water.*

OR

A1C ≥6.5% (48 mmol/‍mol). The test should be per­formed in a lab­o­ra­to­ry using a method that is NGSP cer­ti­fied and stan­dardized to the DCCT assay.*

OR

In a pa­tient with clas­sic symp­toms of hy­per­glycemia or hy­per­glycemic cri­sis, a ran­dom plas­ma glu­cose ≥200 mg/dL (11.1 mmol/‍L).

Table 2.4—Cat­e­gories of in­creased risk for di­a­betes (predi­a­betes)*

FPG 100 mg/dL (5.6 mmol/‍L) to 125 mg/dL (6.9 mmol/‍L) (IFG)

OR

2-h_PG dur­ing 75-g OGTT 140 mg/dL (7.8 mmol/‍L) to 199 mg/dL (11.0 mmol/‍L) (IGT)

OR

A1C 5.7–6.4% (39–47 mmol/‍mol)


* In conditions associated with increased red blood cell turnover, such as sickle cell disease, pregnancy (second and third trimesters), hemodialysis, recent blood loss or transfusion, or erythropoietin therapy, only plasma blood glucose criteria should be used to diagnose diabetes
** For all three tests, risk is continuous, extending below the lower limit of the range and becoming disproportionately greater at the higher end of the range.
***In the absence of unequivocal hyperglycemia, results should be confirmed by repeat testing.
#See table 2.3 for Criteria for testing for diabetes or prediabetes in asymptomatic adults