6.3.0.0 Pre­dic­tors of Hy­po­glycemia

In one study, 84% of pa­tients with an episode of “se­vere hy­po­glycemia” (de- fined as <40 mg/dL [2.2 mmol/‍L]) had a prior episode of hy­po­glycemia (<70 mg/dL [3.9 mmol/‍L]) dur­ing the same ad­mis­sion (55). In an­oth­er study of hy­po­glycemic episodes (defined as <50 mg/dL [2.8 mmol/‍L]), 78% of pa­tients were using basal in­sulin, with the in­ci­dence of hy­po­glycemia peak­ing be­tween mid­night and 6 A.M. De­spite recog­ni­tion of hy­po­glycemia, 75% of pa­tients did not have their dose of basal in­sulin changed be­fore the next in­sulin ad­min­is­tra­tion (56).