2.3.0.0 Treat­ment Goals

2.3.1.0 Rec­om­men­da­tions

Rec­om­men­da­tions

10.3 For pa­tients with di­a­betes and hy­per­ten­sion, blood pres­sure tar­gets should be in­di­vid­u­alized through a shared de­ci­sion-‍mak­ing pro­cess that ad­dress­es car­dio­vas­cu­lar risk, po­ten­tial ad­verse ef­fects of an­ti­hy­per­ten­sive med­i­ca­tions, and pa­tient pref­er­ences. C

10.4 For in­di­vid­u­als with di­a­betes and hy­per­ten­sion at high­er car­dio­vas­cu­lar risk (ex­ist­ing atheroscle­rot­ic car­dio­vas­cu­lar dis­ease or 10-year atheroscle­rot­ic car­dio­vas­cu­lar dis­ease risk >15%), a blood pres­sure tar­get of <130/80 mmHg may be ap­pro­pri­ate, if it can be safe­ly at­tained. C

10.5 For in­di­vid­u­als with di­a­betes and hy­per­ten­sion at lower risk for car­dio­vas­cu­lar dis­ease (10-year atheroscle­rot­ic car­dio­vas­cu­lar dis­ease risk <15%), treat to a blood pres­sure tar­get of <140/90 mmHg. A

10.6 In preg­nant pa­tients with di­a­betes and preex­ist­ing hy­per­ten­sion who are treat­ed with an­ti­hy­per­ten­sive ther­a­py, blood pres­sure tar­gets of 120–160/80–105 mmHg are sug­gest­ed in the in­ter­est of op­ti­miz­ing long-‍term ma­ter­nal health and min­i­miz­ing im­paired fetal growth. E

Ran­dom­ized clin­i­cal tri­als have demon­strat­ed un­equiv­o­cal­ly that treat­ment of hy­per­ten­sion to blood pres­sure <140/90 mmHg re­duces car­dio­vas­cu­lar events as well as mi­crovas­cu­lar com­pli­ca­tions (21-27). There­fore, pa­tients with type 1 or type 2 di­a­betes who have hy­per­ten­sion should, at a min­i­mum, be treat­ed to blood pres­sure tar­gets of <140/90 mmHg. The benefits and risks of in­ten­si­fy­ing an­ti­hy­per­ten­sive ther­a­py to tar­get blood pres­sures lower than <140/90 mmHg (e.g., <130/80 or <120/80 mmHg) have been eval­u­ated in large ran­dom­ized clin­i­cal tri­als and me­ta­ ana­ly­ses of clin­i­cal tri­als. No­tably, there is an ab­sence of high-‍qual­i­ty data avail­able to guide blood pres­sure tar­gets in type 1 di­a­betes.