﻿{"metaInformation":{"toolId":"0000000851","toolVersion":"1.1","toolType":"Dash&shy;board","toolName":"CKD Risk As&shy;sess&shy;ment in Di&shy;a&shy;betes","creationDate":"2025\/Feb\/26","publishedDate":"2025-02-27","expiryDate":"","author":"Shan&shy;tanu Patil","columnList":["Chron&shy;ic Kid&shy;ney Dis&shy;ease Risk As&shy;sess&shy;ment"],"setTimerClock":"false","setPdfbtn":"false","setResetbtn":"true","setCopyRightText":"false","setCustomizeCopyRightText":"false","customizeCopyRightText":"","setMoreInformation":"false","moreInformationLink":"","abbreviated_title":"","synonyms_titles":"","medical_specialty":"105,106,104","medical_device":"","approved_by":"","intended_purposes":"Iden&shy;ti&shy;fy and strat&shy;i&shy;fy CKD risk in pa&shy;tients with di&shy;a&shy;betes Pro&shy;vide rec&shy;om&shy;men&shy;da&shy;tions for CKD mon&shy;i&shy;tor&shy;ing fre&shy;quen&shy;cy based on eGFR and UACR Guide re&shy;fer&shy;ral to nephrol&shy;o&shy;gy for high-risk pa&shy;tients Sup&shy;port ear&shy;ly in&shy;ter&shy;ven&shy;tion strate&shy;gies to slow CKD pro&shy;gres&shy;sion and re&shy;duce car&shy;dio&shy;vas&shy;cu&shy;lar risk","indication":"","prediction":"","caution":"","mathematical_formula":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n<p>Im&shy;age com&shy;ing soon<\/p>\n\n<p>eGFR<sub>cr<\/sub>&nbsp;= 142 x min(S<sub>cr<\/sub>\/&kappa;, 1)<sup>&alpha;<\/sup>&nbsp;x max(S<sub>cr<\/sub>\/&kappa;, 1)<sup>-1.200<\/sup>&nbsp;x 0.9938<sup>Age<\/sup>&nbsp;x 1.012 [if fe&shy;male]<\/p>\n\n<p>where:<\/p>\n\n<p>S<sub>cr<\/sub>&nbsp;= stan&shy;dard&shy;ized serum cre&shy;a&shy;ti&shy;nine in mg\/dL<\/p>\n\n<p>&kappa; = 0.7 (fe&shy;males) or 0.9 (males)<\/p>\n\n<p>&alpha; = -0.241 (fe&shy;male) or -0.302 (male)<\/p>\n\n<p>min(S<sub>cr<\/sub>\/&kappa;, 1) is the min&shy;i&shy;mum of S<sub>cr<\/sub>\/&kappa; or 1.0<\/p>\n\n<p>max(S<sub>cr<\/sub>\/&kappa;, 1) is the max&shy;i&shy;mum of S<sub>cr<\/sub>\/&kappa; or 1.0<\/p>\n\n<p>Age (years)<\/p>\n\n<p>&nbsp;<\/p>\n\n<p>CKD Risk Strat&shy;i&shy;fi&shy;ca&shy;tion Based on eGFR & UACR:<\/p>\n\n<p class=\"listlevel1\">Low Risk (G1-G2, A1) &rarr; An&shy;nu&shy;al Mon&shy;i&shy;tor&shy;ing<\/p>\n\n<p class=\"listlevel1\">Mod&shy;er&shy;ate Risk (G1-G2, A2 or G3a, A1) &rarr; Mon&shy;i&shy;tor 1-2 times\/year<\/p>\n\n<p class=\"listlevel1\">High Risk (G3a, A2 or G3b, A1) &rarr; Mon&shy;i&shy;tor 2-3 times\/year & Con&shy;sid&shy;er Nephrol&shy;o&shy;gy Re&shy;fer&shy;ral<\/p>\n\n<p class=\"listlevel1\">Very High Risk (G3b, A2 or G4-G5, A3) &rarr; Mon&shy;i&shy;tor 4+ times\/year & Nephrol&shy;o&shy;gy Re&shy;fer&shy;ral<\/p>\n\n<p class=\"listlevel1\">eGFR &lt;30 or UACR &gt;300 &rarr; Im&shy;me&shy;di&shy;ate Nephrol&shy;o&shy;gy Re&shy;fer&shy;ra<\/p>\n<\/body>\n<\/html>\n","additional_explanations":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\"><\/body>\n<\/html>\n","interpretation":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\"><\/body>\n<\/html>\n","recommendations":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\"><\/body>\n<\/html>\n","original_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n<p>Amer&shy;i&shy;can Di&shy;a&shy;betes As&shy;so&shy;ci&shy;a&shy;tion Pri&shy;ma&shy;ry Care Ad&shy;vi&shy;so&shy;ry Group. 11. Chron&shy;ic kid&shy;ney dis&shy;ease and risk man&shy;age&shy;ment: Stan&shy;dards of Care in Di&shy;a&shy;betes&mdash;2025 Abridged for Pri&shy;ma&shy;ry Care. Clin Di&shy;a&shy;betes. Pub&shy;lished on&shy;line ahead of print 1 April 2025 (doi: 10.2337\/cd25-a011). &copy;2025 by the Amer&shy;i&shy;can Di&shy;a&shy;betes As&shy;so&shy;ci&shy;a&shy;tion.<\/p>\n<\/body>\n<\/html>\n","validation_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\"><\/body>\n<\/html>\n","other_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\"><\/body>\n<\/html>\n","reference_tool":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\"><\/body>\n<\/html>\n","principleValidated":"false","toolLanguage":"1","setAbbreviation":"true","abbreviation_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n<table class=\"table\">\n\t<tbody>\n\t\t<tr>\n\t\t\t<td>A<\/td>\n\t\t\t<td>Al&shy;bu&shy;min&shy;uria<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>CKD<\/td>\n\t\t\t<td>Chron&shy;ic kid&shy;ney dis&shy;ease<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>G<\/td>\n\t\t\t<td>GFR<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>GFR<\/td>\n\t\t\t<td>Glomeru&shy;lar fil&shy;tra&shy;tion rate<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n\n<p>&nbsp;<\/p>\n<\/body>\n<\/html>\n","setFootnote":"true","footnote_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n<p>Risk of CKD pro&shy;gres&shy;sion, CVD risk, and mor&shy;tal&shy;i&shy;ty; fre&shy;quen&shy;cy of vis&shy;its; and re&shy;fer&shy;ral to nephrol&shy;o&shy;gy ac&shy;cord&shy;ing to GFR and al&shy;bu&shy;min&shy;uria. Num&shy;bers in the box&shy;es are the num&shy;ber of times per year to screen or mon&shy;i&shy;tor. Green re&shy;flects no ev&shy;i&shy;dence of CKD, with screen&shy;ing in&shy;di&shy;cat&shy;ed once per year. Sug&shy;gest&shy;ed mon&shy;i&shy;tor&shy;ing of preva&shy;lent CKD varies from once (yel&shy;low) to four or more times (deep red) per year. Adapt&shy;ed from de Boer IH, Khunti K, Sadusky T, et al. Di&shy;a&shy;betes man&shy;age&shy;ment in chron&shy;ic kid&shy;ney dis&shy;ease: a con&shy;sen&shy;sus re&shy;port by the Amer&shy;i&shy;can Di&shy;a&shy;betes As&shy;so&shy;ci&shy;a&shy;tion (ADA) and Kid&shy;ney Dis&shy;ease: Im&shy;prov&shy;ing Glob&shy;al Out&shy;comes (KDI&shy;GO). Di&shy;a&shy;betes Care 2022;45:3075&ndash;3090.<\/p>\n\n<p>Sug&shy;gest&shy;ed ci&shy;ta&shy;tion: Amer&shy;i&shy;can Di&shy;a&shy;betes As&shy;so&shy;ci&shy;a&shy;tion Pri&shy;ma&shy;ry Care Ad&shy;vi&shy;so&shy;ry Group. 11. Chron&shy;ic kid&shy;ney dis&shy;ease and risk man&shy;age&shy;ment: Stan&shy;dards of Care in Di&shy;a&shy;betes&mdash;2025 Abridged for Pri&shy;ma&shy;ry Care. Clin Di&shy;a&shy;betes. Pub&shy;lished on&shy;line ahead of print 1 April 2025 (doi: 10.2337\/cd25-a011). &copy;2025 by the Amer&shy;i&shy;can Di&shy;a&shy;betes As&shy;so&shy;ci&shy;a&shy;tion.<\/p>\n<\/body>\n<\/html>\n","setToolProfileBtn":"true","indicated_in_patients":"Type 1 Diabetes Mellitus (T1DM) for \u22655 years Type 2 Diabetes Mellitus (T2DM) Hypertension Cardiovascular Disease Anemia Hyperparathyroidism Urinary Albumin-to-Creatinine Ratio (UACR) >30 mg\/g eGFR <60 mL\/min\/1.73m\u00b2","indicated_in_ff_interventions":"Di&shy;a&shy;betes man&shy;age&shy;ment and risk as&shy;sess&shy;ment Chron&shy;ic Kid&shy;ney Dis&shy;ease (CKD) screen&shy;ing and mon&shy;i&shy;tor&shy;ing Re&shy;fer&shy;ral to nephrol&shy;o&shy;gy based on risk strat&shy;i&shy;fi&shy;ca&shy;tion Guid&shy;ance on SGLT2 in&shy;hibitors and CKD-spe&shy;cif&shy;ic treat&shy;ments","predicted_outcomes":"","prediction_period":"","setScoreWarningText":"false","setCustomizeWarningText":"false","customizeWarningText":"","setBlueHighlightForInput":"false","setRecommendationRejection":"false","setFeedbackButton":"false","setMindMapAvailable":"false","setDocumentStatus":"false","setToolTestedStatus":"false","tool_development_supported_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\"><\/body>\n<\/html>\n","promo_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Doc&shy;u&shy;ment<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n<p>This Clin&shy;i&shy;cal De&shy;ci&shy;sion Sup&shy;port (CDS) tool eval&shy;u&shy;ates the risk of Chron&shy;ic Kid&shy;ney Dis&shy;ease (CKD) pro&shy;gres&shy;sion, car&shy;dio&shy;vas&shy;cu&shy;lar risk, and nephrol&shy;o&shy;gy re&shy;fer&shy;ral needs based on es&shy;ti&shy;mat&shy;ed Glomeru&shy;lar Fil&shy;tra&shy;tion Rate (eGFR, cal&shy;cu&shy;lat&shy;ed us&shy;ing the CKD-EPI Re&shy;fit Equa&shy;tion) and Uri&shy;nary Al&shy;bu&shy;min-to-Cre&shy;a&shy;ti&shy;nine Ra&shy;tio (UACR). The tool is de&shy;signed for pa&shy;tients with di&shy;a&shy;betes (T1DM or T2DM) and oth&shy;er CKD risk fac&shy;tors.<\/p>\n<\/body>\n<\/html>\n","sub_title":"Clin&shy;i&shy;cal De&shy;ci&shy;sion Sup&shy;port (CDS) Tool for CKD Risk Strat&shy;i&shy;fi&shy;ca&shy;tion in Di&shy;a&shy;betes","feedback_link":"","feedback_option":"","feedback_email":"","selected_tool_type":"cdss","index_term":"CKD Risk As&shy;sess&shy;ment in Di&shy;a&shy;betes","full_text":"","tool_category":"9","translatedLanguages":"","primary_medical_specialty":"105","restorationCompatibleVersions":"","releaseVersion":"NR","releaseDate":"","releaseMode":"1","publishedBy":"B&ouml;rm Bruck&shy;meier Ver&shy;lag GmbH"}}