Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nTable: Features of medications for lowering glucose in type 2 diabetes<\/span><\/p>\n\n<img alt=\"\" src=\"\/cdst_editor\/exports\/dashboard_0000000659\/1.4\/images\/Table_9_2(1).png\" style=\"width: 100%;\" \/><\/p>\n\nCKD, chronic kidney disease; CV, cardiovascular; DKA, diabetic ketoacidosis; DPP-4, dipeptidyl peptidase 4; eGFR, estimated glomerular filtration rate; FDA, U.S. Food and Drug Administration; GI, gastrointestinal; GIP, glucose-dependent insulinotropic polypeptide; GLP-1 RA, glucagon-like peptide 1 receptor agonist; HF, heart failure; MACE, major adverse cardiovascular events; MASH, metabolic dysfunction- associated steatohepatitis; SGLT2, sodium–glucose cotransporter 2; SQ, subcutaneous; T2D, type 2 diabetes.<\/p>\n\n*For agent-specific dosing recommendations, please refer to manufacturers’ prescribing information.<\/p>\n\n1<\/span>Tsapas et al (107).<\/p>\n\n2<\/span>Tsapas et al (317).<\/p>\n\nAdapted from Davies et al (90).<\/p>\n<\/body>\n<\/html>\n","additional_explanations":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","interpretation":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","recommendations":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","original_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nAmerican Diabetes Association Professional Practice Committee, \"Pharmacologic approaches to glycemic treatment: Standards of Care in Diabetes-2026\", Diabetes Care<\/span>, vol. 49, Suppl. 1, pp. S183–S215.<\/p>\n<\/body>\n<\/html>\n","validation_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","other_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","reference_tool":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","principleValidated":"false","toolLanguage":"1","setAbbreviation":"true","abbreviation_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n<table class=\"table\">\n\t<tbody>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tCKD<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tChronic kidney disease<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tCV<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tCardiovascular<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tDKA<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tDiabetic ketoacidosis<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tDPP-4<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tDipeptidyl peptidase 4<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\teGFR<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tEstimated glomerular filtration rate<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tFDA<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tU.S. Food and Drug Administration<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tGI<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tGastrointestinal<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tGIP<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tGlucose-dependent insulinotropic polypeptide<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tGLP-1 RA<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tGlucagon-like peptide 1 receptor agonist<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tHF<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tHeart failure<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tMACE<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tMajor adverse cardiovascular events<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tMASH<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tMetabolic dysfunction-associated steatohepatitis<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tSGLT2<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tSodium–glucose cotransporter 2<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tSQ<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tSubcutaneous<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tT2D<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tType 2 diabetes<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n<\/body>\n<\/html>\n","setFootnote":"true","footnote_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n*<\/sup>For agent-specific dosing recommendations, please refer to manufacturers’ prescribing information.<\/p>\n\n1<\/sup>Tsapas et al. (107).<\/p>\n\n2<\/sup>Tsapas et al. (317).<\/p>\n\nAdapted from Davies et al. (90).<\/p>\n<\/body>\n<\/html>\n","setToolProfileBtn":"true","indicated_in_patients":"Tye 2 diabetes","indicated_in_ff_interventions":"NA","predicted_outcomes":"NA","prediction_period":"NA","setScoreWarningText":"true","setCustomizeWarningText":"false","customizeWarningText":"","releaseVersion":"NR","releaseDate":"","releaseMode":"1","publishedBy":"Börm Bruckmeier Verlag GmbH","medical_device":"","restorationCompatibleVersions":"","primary_medical_specialty":"106","index_term":"Drug-specific & pt. factors in T2DM Tx [tool]","full_text":"","tool_category":"9","setBlueHighlightForInput":"false","setFeedbackButton":"false","setMindMapAvailable":"false","setDocumentStatus":"false","setRecommendationRejection":"false","tool_development_supported_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\"><\/body>\n<\/html>\n","promo_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\">\nThis tool provides an overview of glucose-lowering medications used in the management of type 2 diabetes, including their mechanisms of action, efficacy, benefits, and potential side effects. It is based on recent guidelines and consensus reports from the American Diabetes Association and European Association for the Study of Diabetes.<\/p>\n<\/body>\n<\/html>\n","setToolTestedStatus":"false","translatedLanguages":"","sub_title":"A summary of medications for lowering glucose based on American Diabetes Association Guidelines"}}

{"metaInformation":{"toolId":"0000000659","toolVersion":"1.7","toolType":"Dashboard","toolName":"Medications for Lowering Glucose, Summary of Characteristics","creationDate":"2023\/Dec\/01","publishedDate":"2025-12-10","expiryDate":"","author":"Soumyavani Pappu","columnList":["Features of Medications"],"setTimerClock":"false","setPdfbtn":"false","setResetbtn":"true","setCopyRightText":"false","setCustomizeCopyRightText":"false","customizeCopyRightText":"","setMoreInformation":"true","moreInformationLink":"ref_ENAS7246_4.3.0.0.html","abbreviated_title":"NA","synonyms_titles":"NA","medical_specialty":"105,106","approved_by":"NA","intended_purposes":"To guide healthcare providers in selecting and managing glucose-lowering medications for patients with type 2 diabetes based on current evidence and patient-specific factors","indication":"","prediction":"","caution":"NA","mathematical_formula":"\n\n\n\tDocument<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nTable: Features of medications for lowering glucose in type 2 diabetes<\/span><\/p>\n\n<img alt=\"\" src=\"\/cdst_editor\/exports\/dashboard_0000000659\/1.4\/images\/Table_9_2(1).png\" style=\"width: 100%;\" \/><\/p>\n\nCKD, chronic kidney disease; CV, cardiovascular; DKA, diabetic ketoacidosis; DPP-4, dipeptidyl peptidase 4; eGFR, estimated glomerular filtration rate; FDA, U.S. Food and Drug Administration; GI, gastrointestinal; GIP, glucose-dependent insulinotropic polypeptide; GLP-1 RA, glucagon-like peptide 1 receptor agonist; HF, heart failure; MACE, major adverse cardiovascular events; MASH, metabolic dysfunction- associated steatohepatitis; SGLT2, sodium–glucose cotransporter 2; SQ, subcutaneous; T2D, type 2 diabetes.<\/p>\n\n*For agent-specific dosing recommendations, please refer to manufacturers’ prescribing information.<\/p>\n\n1<\/span>Tsapas et al (107).<\/p>\n\n2<\/span>Tsapas et al (317).<\/p>\n\nAdapted from Davies et al (90).<\/p>\n<\/body>\n<\/html>\n","additional_explanations":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","interpretation":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","recommendations":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","original_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nAmerican Diabetes Association Professional Practice Committee, \"Pharmacologic approaches to glycemic treatment: Standards of Care in Diabetes-2026\", Diabetes Care<\/span>, vol. 49, Suppl. 1, pp. S183–S215.<\/p>\n<\/body>\n<\/html>\n","validation_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","other_reference":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","reference_tool":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\nNA<\/p>\n<\/body>\n<\/html>\n","principleValidated":"false","toolLanguage":"1","setAbbreviation":"true","abbreviation_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n<table class=\"table\">\n\t<tbody>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tCKD<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tChronic kidney disease<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tCV<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tCardiovascular<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tDKA<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tDiabetic ketoacidosis<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tDPP-4<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tDipeptidyl peptidase 4<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\teGFR<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tEstimated glomerular filtration rate<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tFDA<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tU.S. Food and Drug Administration<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tGI<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tGastrointestinal<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tGIP<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tGlucose-dependent insulinotropic polypeptide<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tGLP-1 RA<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tGlucagon-like peptide 1 receptor agonist<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tHF<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tHeart failure<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tMACE<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tMajor adverse cardiovascular events<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tMASH<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tMetabolic dysfunction-associated steatohepatitis<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tSGLT2<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tSodium–glucose cotransporter 2<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tSQ<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tSubcutaneous<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t\t<tr>\n\t\t\t<td>\n\t\t\tT2D<\/p>\n\t\t\t<\/td>\n\t\t\t<td>\n\t\t\tType 2 diabetes<\/p>\n\t\t\t<\/td>\n\t\t<\/tr>\n\t<\/tbody>\n<\/table>\n<\/body>\n<\/html>\n","setFootnote":"true","footnote_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/dashboard_maker\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/dashboard_maker\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/svc.webspellchecker.net\/spellcheck31\/wscbundle\/css\/wsc.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\" data-wsc-instance=\"true\">\n*<\/sup>For agent-specific dosing recommendations, please refer to manufacturers’ prescribing information.<\/p>\n\n1<\/sup>Tsapas et al. (107).<\/p>\n\n2<\/sup>Tsapas et al. (317).<\/p>\n\nAdapted from Davies et al. (90).<\/p>\n<\/body>\n<\/html>\n","setToolProfileBtn":"true","indicated_in_patients":"Tye 2 diabetes","indicated_in_ff_interventions":"NA","predicted_outcomes":"NA","prediction_period":"NA","setScoreWarningText":"true","setCustomizeWarningText":"false","customizeWarningText":"","releaseVersion":"NR","releaseDate":"","releaseMode":"1","publishedBy":"Börm Bruckmeier Verlag GmbH","medical_device":"","restorationCompatibleVersions":"","primary_medical_specialty":"106","index_term":"Drug-specific & pt. factors in T2DM Tx [tool]","full_text":"","tool_category":"9","setBlueHighlightForInput":"false","setFeedbackButton":"false","setMindMapAvailable":"false","setDocumentStatus":"false","setRecommendationRejection":"false","tool_development_supported_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\"><\/body>\n<\/html>\n","promo_text":"<!DOCTYPE html>\n<html lang=\"\">\n<head><meta charset=\"UTF-8\"><meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n\t<title>Document<\/title>\n\t<link href=\"\/cdst_editor\/media\/css\/temp.css\" rel=\"stylesheet\" \/>\n\t<link href=\"https:\/\/cpms.bbinfotech.com\/cdst_editor\/media\/lib\/ckeditor\/plugins\/tableselection\/styles\/tableselection.css\" rel=\"stylesheet\" type=\"text\/css\" \/>\n<\/head>\n<body class=\"extraInfoForRule\">\nThis tool provides an overview of glucose-lowering medications used in the management of type 2 diabetes, including their mechanisms of action, efficacy, benefits, and potential side effects. It is based on recent guidelines and consensus reports from the American Diabetes Association and European Association for the Study of Diabetes.<\/p>\n<\/body>\n<\/html>\n","setToolTestedStatus":"false","translatedLanguages":"","sub_title":"A summary of medications for lowering glucose based on American Diabetes Association Guidelines"}}