2.4.0.0 Treat­ment Strate­gies

2.4.1.0 Lifestyle In­ter­ven­tion

Rec­om­men­da­tions

10.7 For pa­tients with blood pres­sure >120/80 mmHg, lifestyle in­ter­ven­tion con­sists of weight loss if over­weight or obese, a Di­etary Ap­proach­es to Stop Hy­per­ten­sion (DASH)-‍style di­etary pat­tern in­clud­ing re­duc­ing sodi­um and in­creas­ing potas­si­um in­take, mod­er­a­tion of al­co­hol in­take, and in­creased phys­i­cal ac­tiv­i­ty. B

Lifestyle man­age­ment is an im­por­tant com­po­nent of hy­per­ten­sion treat­ment be­cause it low­ers blood pres­sure, en­hances the ef­fec­tiveness of some an­ti­hy­per­ten­sive med­i­ca­tions, pro­motes other as­pects of metabol­ic and vas­cu­lar health, and gen­er­ally leads to few ad­verse ef­fects. Lifestyle ther­a­py con­sists of re­duc­ing ex­cess body weight through caloric re­stric­tion, re­strict­ing sodi­um in­take (<2,300 mg/‍day), in­creas­ing con­sump­tion of fruits and veg­eta­bles (8–10 serv­ings per day) and low-‍fat dairy prod­ucts (2–3 serv­ings per day), avoid­ing ex­cessive al­co­hol con­sump­tion (no more than 2 serv­ings per day in men and no more than 1 serv­ing per day in women) (46), and in­creas­ing ac­tiv­i­ty lev­els (47).

These lifestyle in­ter­ven­tions are rea­son­able for in­di­vid­u­als with di­a­betes and mild­ly el­e­vat­ed blood pres­sure (sys­tolic >120 mmHg or di­as­tolic >80 mmHg) and should be ini­ti­at­ed along with phar­ma­co­log­ic ther­a­py when hy­per­ten­sion is di­ag­nosed (Fig. 10.1) (47). A lifestyle ther­a­py plan should be de­vel­oped in col­lab­o­ra­tion with the pa­tient and dis­cussed as part of di­a­betes man­age­ment.

Figure 10.1—Recommendations for the treatment of confirmed hypertension in people with diabetes

Fig­ure 10.1—Rec­om­men­da­tions for the treat­ment of confirmed hy­per­ten­sion in peo­ple with di­a­betes.

*An ACE in­hibitor (ACEi) or an­giotensin re­cep­tor block­er (ARB) is sug­gest­ed to treat hy­per­ten­sion for pa­tients with urine albumin-to-cre­a­ti­nine ratio 30–299 mg/g cre­a­ti­nine and strong­ly rec­om­mend­ed for pa­tients with urine albumin-to-cre­a­ti­nine ratio ≥300 mg/g cre­a­ti­nine.

**Thi­azide-‍like di­uret­ic; long-‍act­ing agents shown to re­duce car­dio­vas­cu­lar events, such as chlort­ha­li­do­ne and in­da­pamide, are pre­ferred.

***Di­hy­dropy­ri­dine cal­ci­um chan­nel block­er (CCB). BP, blood pres­sure. Adapt­ed from de Boer et al. (17).

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