Rec­om­men­da­tions

2.4 Plas­ma blood glu­cose rather than A1C should be used to di­ag­nose the acute onset of type 1 di­a­betes in in­di­vid­u­als with symp­toms of hy­per­glycemia. E

2.5 Screen­ing for type 1 di­a­betes risk with a panel of au­toan­ti­bod­ies is cur­rently rec­om­mend­ed only in the set­ting of a re­search trial or in first-‍de­gree fam­i­ly mem­bers of a proband with type 1 di­a­betes. B

2.6 Per­sis­tence of two or more au­toan­ti­bod­ies pre­dicts clin­i­cal di­a­betes and may serve as an in­di­ca­tion for in­ter­ven­tion in the set­ting of a clin­i­cal trial. B